Sci-Tech

My team has developed a series of gene chips for cattle

2025-07-22   

On the 21st, it was learned from the National Dairy Technology Innovation Center that the center's technology research and development team has successfully developed a genetic evaluation chip for dairy cow embryo genomes and a "high-yield, disease resistant, and longevity" function enhanced genome prediction chip. This series of gene chips has completely independent intellectual property rights, filling the gap in genetic evaluation technology for gene chip testing in China. Gene chip is a high-throughput bioinformatics analysis method based on microarray technology, which can be used to detect the location, content, type, etc. of functional genes related to production performance, and has the characteristics of high-throughput, high sensitivity, and high specificity. Previously, this technology has been widely used in dairy cattle breeding in developed countries such as Europe and the United States to shorten generation intervals and accelerate the genetic improvement process of dairy cows. This project relies on 96 large-scale ranches and over 600000 dairy cows nationwide to establish a big data platform for dairy breeding. It conducts genomic testing and establishes health and production records for cattle with good milk production economy and high health. Through machine learning and algorithm models, the team identified and evaluated massive amounts of genetic data and trait phenotypes, successfully deciphering the genetic fingerprints of world-class dairy cattle breeds and Chinese regional cattle breeds. They designed a genetic evaluation chip for dairy cattle embryos and a "high-yield, disease resistant, and longevity" function enhanced genome prediction chip, ensuring that cows can produce high-quality milk with "high protein, excellent fat, low somatic cell count, and low total bacterial count" after chip testing. It is reported that compared with whole genome sequencing, using this series of chips for genetic testing of cows can increase detection efficiency by more than 4 times, and the cost is only one-fifth of whole genome sequencing. Next, the National Dairy Technology Innovation Center will focus on cultivating localized new strains of Chinese dairy cows and launch a series of functional enhanced gene detection chips to balance cow breeding, milk production, and health indicators. At the same time, it will explore genetic genes with low carbon emissions, heat stress resistance, and distinctive flavors, develop targeted gene chips, promote the refinement and personalized development of dairy breeding, continuously improve the quality of Chinese dairy cow strains, and achieve independent and controllable dairy cow sources. (New Society)

Edit:XunTing Responsible editor:LiuKaiEn

Source:Science and Technology Daily

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