Scientists from Rutgers University New Brunswick and other institutions in the United States have published important research results in the latest issue of academic journals, revealing for the first time the important mechanism by which the key brain protein cytochrome maintains brain cell connections. This discovery opens up a new path for the treatment of neurodegenerative diseases such as Parkinson's disease and Alzheimer's disease. The research team has made three key discoveries: Cypin protein can add special "localization markers" to proteins within synapses, just like attaching address labels to express packages, ensuring that proteins accurately arrive at their working positions; Cypin can bind to proteasomes responsible for protein breakdown, moderately slowing down the rate of protein breakdown. This "braking effect" allows important proteins to accumulate, thereby promoting communication between neurons; The presence of Cypin significantly increases the levels of key proteins within synapses and activates the UBE4A protein. This dual effect is like simultaneously upgrading the hardware and software of communication devices, greatly improving the communication efficiency of brain cells. These findings provide a new approach for treating neurodegenerative diseases. By targeting the regulation of cytochrome proteins, it is expected to repair damaged brain cell connectivity networks and regain the key to memory and thinking. The team emphasizes that neuroscience research is still in its basic stage, but the core role of cytochrome protein in synaptic plasticity makes it an ideal target for combating diseases such as Alzheimer's disease. When neurodegenerative diseases cause synaptic "signal interruption", therapies based on Cypin may become a powerful tool for rebuilding the "communication network" of brain cells. (New Society)