Reporters learned from the Aerospace Information Innovation Institute of the Chinese Academy of Sciences (hereinafter referred to as the "Academy") on the 28th that the National Key Laboratory of Sensor Technology of the Academy and the First Affiliated Hospital of Harbin Medical University jointly completed the clinical trial of "precise localization of brain deep tumor boundary based on implantable microelectrode array". This is the world's first clinical trial of using brain computer interfaces for precise boundary positioning during deep brain tumor surgery, marking an important breakthrough in China's independently developed implantable clinical brain computer interface technology. This clinical trial used the NeuroDepth clinical brain computer interface microelectrode independently developed by the Aerospace Academy, as well as the AIRCAS-128 multi-level regulation and high-throughput neural signal synchronous detector. The former obtains high-precision tumor boundary feature signals through real-time signal detection; The latter can synchronously collect and analyze massive neural signals, convert the raw signals captured by electrodes into accurate "lesion navigation", and provide real-time data for tumor intraoperative boundary judgment. This technology not only breaks through the limitation of traditional neural electrodes that can only detect the surface and superficial layers of the brain, but can also detect any area of the entire brain including the surface, superficial brain, and deep brain; It can also synchronously detect chemical signals such as dopamine, glutamate and other neurotransmitters, providing a more comprehensive basis for distinguishing tumor tissue from normal tissue. ”Wang Mixia, a specially appointed research backbone and associate researcher at the Aerospace Academy, introduced that this will help to scientifically carry out surgical planning, accurately remove malignant tumors, and protect functional areas such as brain movement, language, and cognition. This clinical trial was conducted on a glioma patient. The patient experienced frequent seizures due to compression from a brain tumor before surgery. We combined imaging data and used real-time feedback of single-cell level neural signals from NeuroDepth to accurately identify tumor boundaries. While maximizing the protection of functional areas, we successfully removed the tumor completely. ”Shi Huaizhang, Director of Neurosurgery at the First Affiliated Hospital of Harbin Medical University, said. Academician Wu Yirong, Academic Dean of the Aerospace Academy and Director of the Academic Committee of the National Key Laboratory of Sensor Technology, stated that the success of this clinical trial is a crucial step for the clinical translation and industrial development of brain computer interface technology. (New Society)