The Karolinska Institute in Sweden has collaborated with scientists from Yale University in the United States to develop a new blood testing technology called "Systematic Age Detection Method", which can comprehensively evaluate the aging status of 11 different physiological systems in the human body through a single blood draw, providing more accurate basis for personalized health management. The relevant research results were published in the latest issue of the journal Nature Aging. The aging rate of various organs and systems in the human body is not consistent, and is influenced by multiple factors such as genetics, environment, and lifestyle. Traditional biological age detection methods can only provide a holistic value and cannot reflect the differences in aging in different parts. The new method is based on the DNA methylation mechanism in epigenetics. By analyzing the association between specific biomarkers in the blood (such as cholesterol, blood glucose, etc.) and age-related diseases in various organs, combined with machine learning technology, a predictive model that can evaluate the age of 11 physiological systems including the heart, lungs, brain, metabolic system, and immune system is established. The research team first analyzed the health data of about 7500 people, and then validated the model using over 8000 blood samples. The results showed that compared with the traditional epigenetic clock, the new method can not only more accurately predict specific diseases related to aging such as heart disease, but also reveal significant differences in aging patterns of various systems within different individuals. The team stated that this detection technology can provide more targeted intervention guidance for clinical practice. For example, if a test finds that someone's immune system is significantly older than their heart or lungs, doctors can recommend measures to enhance their immune function; If the aging score of the cardiac system is high, early intervention can be achieved by adjusting lifestyle or medication. The launch of this detection technology marks a new stage in aging assessment from "overall age" to "systematic age", providing a scientific tool for achieving personalized anti-aging and health management. (New Society)