Attention, these five medications should not be taken on an empty stomach: 1. Antibiotics (amoxicillin, cephalosporins): It is safer to take them one hour after meals. If taken on an empty stomach, the medication may come into direct contact with the stomach wall, causing symptoms such as nausea, vomiting, diarrhea, and in severe cases, dehydration. Correct method: It is recommended to take it one hour after meals. 2、 Antibacterial drug (metronidazole): Taking it one hour after a meal and seven days after quitting drinking can easily irritate the stomach, causing nausea, dizziness, and even drug-induced gastritis. Correct method: Strictly follow the "take 1 hour after meals" rule, and absolutely prohibit drinking alcohol (including alcoholic beverages and food) within 7 days after stopping the medication. 3、 Non steroidal anti-inflammatory drugs (ibuprofen, aspirin): When taken on an empty stomach half an hour after a meal and avoiding fruit juice and coffee, the drugs can stimulate the stomach wall like a "scratch", which can easily cause stomach pain and ulcers, and may increase the risk of gastric bleeding in the long run. Correct method: Take half an hour after meals, choose warm water when taking, and avoid drinks such as fruit juice and coffee. 4、 Hypoglycemic drug (metformin): chewed with the first bite of food, reducing side effects by 80%. If taken on an empty stomach or for a long time after a meal, it may cause discomfort such as bloating, diarrhea, nausea, and in severe cases, electrolyte imbalance. Correct method: It is recommended to chew it with the first bite of food (or take it with a meal). Clinical data shows that chewing with meals can reduce gastrointestinal side effects by about 80%. 5、 Vitamin B group: Eat with meals after breakfast, and it is easier to absorb with carbohydrates. Vitamin B group is a water-soluble vitamin. When taken on an empty stomach, the medication quickly enters the intestines through the stomach and is not fully absorbed, and is excreted in the urine. Correct method: Take with meals after breakfast (such as pairing with carbohydrates like bread and buns) to prolong the medication's stay in the stomach and promote absorption. (New Society)